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Targets Recommended: HCV Protease HBV JAK IFNAR STAT

2

抑制剂 & 化合物

18

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T22142 RO8191

RO4948191,CDM-3008

HCV Protease; HBV; JAK; IFNAR; STAT Angiogenesis; Chromatin/Epigenetic; Immunology/Inflammation; JAK/STAT signaling; Microbiology/Virology; Proteases/Proteasome; Stem Cells
RO8191 (CDM-3008) 是干扰素 (IFN) 受体激动剂。它直接与 IFNα/β 受体 2 结合,激活 IFN 刺激的基因表达和 JAK/STAT 磷酸化。它通过具有干扰素样活性发挥 cccDNA 调节剂作用,并具有抗 HBV 活性。
T38161 STING Agonist C11

STING Agonist C11

STING agonist C11 is an agonist of the stimulator of interferon genes (STING) pathway.1 It induces secretion of type I IFN from THF and MM6 cells when used at a concentration of 50 μM. STING agonist C11 induces phosphorylation of IFN regulatory factor 3 (IRF3) and increases expression of IFIT1 and viperin, but not IL-1β, IL-6, or IL-8 in THF cells in a STING-dependent manner. It reduces viral titers of chikungunya, Venezuelan equine encephalitis, o'nyong-nyong, Mayaro, and Ross River viruses gro...

化合物

RO8191
Cat.No: T22142
Synonym: RO4948191,CDM-3008
Target: HCV Protease, HBV, JAK, IFNAR, STAT
STING Agonist C11
Cat.No: T38161
Synonym: STING Agonist C11
Target:
Cat. No. Product Name Species Expression System
TMPY-00638 Interferon alpha B/IFNA8 Protein, Human, Recombinant (His)

IFN-αB,IFN-alphaB,interferon<...

Human HEK293 Cells
Interferon alpha B/IFNA8 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.9 kDa and the accession number is A0A7R8C381.
TMPY-02647 IFNAR1 Protein, Human, Recombinant (His)

interferon (alpha, beta and omega) recepto...

Human HEK293 Cells
IFNAR1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48.6 kDa and the accession number is P17181-1.
TMPY-04799 IFNAR2 Protein, Human, Recombinant (His), Biotinylated

IFN-R,interferon (α, β and Ω) receptor 2,I...

Human HEK293 Cells
IFNAR2 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.2 kDa and the accession number is P48551-1.
TMPY-03637 Interferon alpha B/IFNA8 Protein, Cynomolgus, Recombinant (His)

Interferon α-B,interferon

Cynomolgus HEK293 Cells
Interferon alpha B/IFNA8 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43 kDa and the accession number is G7PS89.
TMPY-03620 Interferon alpha B/IFNA8 Protein, Cynomolgus, Recombinant (mFc)

Interferon α-B,interferon

Cynomolgus HEK293 Cells
Interferon alpha B/IFNA8 Protein, Cynomolgus, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 46 kDa and the accession number is G7PS89.
TMPY-03648 Interferon alpha B/IFNA8 Protein, Human, Recombinant

IFN-αB,IFN-alphaB,interferon<...

Human HEK293 Cells
Interferon alpha B/IFNA8 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 38 kDa and the accession number is A0A7R8C381.
TMPY-04254 IFNAR1 Protein, Rhesus, Recombinant (His)

interferon (alpha, beta and omega) recepto...

Rhesus HEK293 Cells
IFNAR1 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48.7 kDa and the accession number is H9Z8H4.
TMPY-03829 IFNAR1 Protein, Rhesus, Recombinant (hFc)

interferon (α, β and Ω) receptor 1,int...

Rhesus HEK293 Cells
IFNAR1 Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 74.5 kDa and the accession number is H9Z8H4.
TMPY-00139 IFNAR2 Protein, Cynomolgus, Recombinant (His)

interferon (α, β and Ω) receptor 2,int...

Cynomolgus HEK293 Cells
IFNAR2 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.3 kDa and the accession number is XP_005548871.1.
TMPY-03927 IFNAR1 Protein, Rhesus, Recombinant

interferon (α, β and ω) receptor 1,int...

Rhesus HEK293 Cells
IFNAR1 Protein, Rhesus, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 48.3 kDa and the accession number is H9Z8H4.
TMPY-01642 IFNAR2 Protein, Human, Recombinant (His)

IFNARB,IFNABR,interferon (α

Human HEK293 Cells
IFNAR2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.2 kDa and the accession number is P48551-1.
TMPY-01640 IFNAR2 Protein, Human, Recombinant (hFc)

interferon (α, β and ω) receptor 2,IFNA

Human HEK293 Cells
IFNAR2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.8 kDa and the accession number is P48551-1.
TMPY-02634 IFNAR1 Protein, Human, Recombinant (hFc)

interferon (α, β and Ω) receptor 1,IFN...

Human HEK293 Cells
IFNAR1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 74 kDa and the accession number is P17181-1.
TMPY-01489 IFNAR1 Protein, Mouse, Recombinant (His)

Ifrc,Ifar,CD118,interferon (α, β and ω) re...

Mouse HEK293 Cells
IFNAR1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47 kDa and the accession number is P33896.
TMPJ-00331 IFNAR1 Protein, Rhesus macaque, Recombinant (His)

IFN-al,CRF2-1,IFN-alpha/beta receptor 1,human i...

Rhesus HEK293 Cells
Interferon‑alpha/beta receptor 1 (IFN‑ alpha / beta R1), also known as IFNAR1, are present in all tissues and even on the surface of most IFN-resistant cells. Isoform 1, isoform 2 and isoform 3 are expressed in the IFN-alpha sensitive myeloma cell line U266B1. Isoform 2 and isoform 3 are expressed in the IFN-alpha resistant myeloma cell line U266R. Isoform 1 is not expressed in IFN-alpha resistant myeloma cell line U266R. It interacts with STAT1 and STAT2, the interaction requires its phosphory...
TMPK-01413 H-2K (b) &B2M&OVA (SIINFEKL) Monomer Protein, Mouse, MHC (His & Avi)

H-2K,OVA,MHC,H2-K1

Mouse HEK293 Cells
Ovalbumin (OVA) has been historically a popular source of such antigens, since OVA can induce both humoral and cellular immune responses based on well-characterised peptide epitopes. The OVA257-264 octapeptide was one of the frst OVA epitopes to be characterised, it has an amino acid sequence SIINFEKL, which is recognised by cytotoxic T lymphocytes. SIINFEKL forms fbrillar assemblies similar to other peptide hydrogels. Te immunoactive properties of this peptide can therefore be related to its se...
TMPK-01412 HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi)

SARS-CoV-2 epitope,MHC

Human HEK293 Cells
HLA-B*15:01 is strongly associated with asymptomatic infection with SARS-CoV-2 and is likely to be involved in the mechanism underlying early viral clearance. T cells from pre-pandemic individuals carrying HLA-B*15:01 were reactive to the immunodominant SARS-CoV-2 S-derived peptide NQKLIANQF, and 100% of the reactive cells displayed memory phenotype.
TMPK-01416 HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi), Biotinylated

MHC,SARS-CoV-2 epitope

Human HEK293 Cells
HLA-B*15:01 is strongly associated with asymptomatic infection with SARS-CoV-2 and is likely to be involved in the mechanism underlying early viral clearance. T cells from pre-pandemic individuals carrying HLA-B*15:01 were reactive to the immunodominant SARS-CoV-2 S-derived peptide NQKLIANQF, and 100% of the reactive cells displayed memory phenotype.

重组蛋白

Interferon alpha B/IFNA8 Protein, Human, Recombinant (His)
Cat.No: TMPY-00638
Species: Human
Expression System: HEK293 Cells
IFNAR1 Protein, Human, Recombinant (His)
Cat.No: TMPY-02647
Species: Human
Expression System: HEK293 Cells
IFNAR2 Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-04799
Species: Human
Expression System: HEK293 Cells
Interferon alpha B/IFNA8 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPY-03637
Species: Cynomolgus
Expression System: HEK293 Cells
Interferon alpha B/IFNA8 Protein, Cynomolgus, Recombinant (mFc)
Cat.No: TMPY-03620
Species: Cynomolgus
Expression System: HEK293 Cells
Interferon alpha B/IFNA8 Protein, Human, Recombinant
Cat.No: TMPY-03648
Species: Human
Expression System: HEK293 Cells
IFNAR1 Protein, Rhesus, Recombinant (His)
Cat.No: TMPY-04254
Species: Rhesus
Expression System: HEK293 Cells
IFNAR1 Protein, Rhesus, Recombinant (hFc)
Cat.No: TMPY-03829
Species: Rhesus
Expression System: HEK293 Cells
IFNAR2 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPY-00139
Species: Cynomolgus
Expression System: HEK293 Cells
IFNAR1 Protein, Rhesus, Recombinant
Cat.No: TMPY-03927
Species: Rhesus
Expression System: HEK293 Cells
IFNAR2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01642
Species: Human
Expression System: HEK293 Cells
IFNAR2 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-01640
Species: Human
Expression System: HEK293 Cells
IFNAR1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-02634
Species: Human
Expression System: HEK293 Cells
IFNAR1 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01489
Species: Mouse
Expression System: HEK293 Cells
IFNAR1 Protein, Rhesus macaque, Recombinant (His)
Cat.No: TMPJ-00331
Species: Rhesus
Expression System: HEK293 Cells
H-2K (b) &B2M&OVA (SIINFEKL) Monomer Protein, Mouse, MHC (His & Avi)
Cat.No: TMPK-01413
Species: Mouse
Expression System: HEK293 Cells
HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01412
Species: Human
Expression System: HEK293 Cells
HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01416
Species: Human
Expression System: HEK293 Cells
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